Two titles are on the line when the UFC returns to Madison Square Garden for UFC 334. The main event will see Ciryl Gane defend the UFC heavyweight title against Josh Hokit.

Gane (14-2, 1 NC) won the interim UFC heavyweight title at the White House against Alex Pereira. He was promoted after Tom Aspinall, who he poked in the eyes at UFC 321, relinquished the belt. The colorful Hokit (10-0) beat Curtis Blaydes in an entertaining fight and knocked out Derrick Lewis to secure a shot at gold.

The co-main event will see a dream fight between Kayla Harrison and Amanda Nunes for the UFC bantamweight title. A two-time Olympic gold medalist, Harrison (19-1) beat Julianna Pena in 2025 for the belt. She recently healed from a neck injury. A former UFC bantamweight and featherweight champion, Nunes (23-5) returns to action after retiring in 2023.

Also on the card, Caio Borralho and Kevin Holland look to entertain against dangerous opponents.

The Sporting News breaks down everything you need to know to bet on the UFC 334 main card, including odds for each fight, the most popular betting markets and best bets. Plus, new users can bet $10 on the card and get $200 in Bonus Bets win or lose at bet365 Sportsbook.

MORE: Breaking down the best UFC betting sites

How to bet on UFC 334

Betting on the UFC 334 fight card is simple. First,  choose a sportsbook to bet with. DraftKings, FanDuel, BetMGM, bet365, theScore Bet, and Fanatics all offer odds on the entire UFC 334 fight card.

1. Choose your sportsbook

Once you choose your sportsbook, you can claim a welcome bonus. First, sign up and enter your verification information, such as your name, address, Social Security number, and other details. Once your account is confirmed, you can claim a welcome bonus from one of the sportsbooks below.

2. Learn the main MMA bet types

You can bet on MMA in several ways, including popular bet types. Moneylines let users pick an outright winner and profit if their fighter wins. Total round betting lets bettors call their own shot on how many rounds a fight will last. Prop betting offers niche markets that any MMA bettor could want.

3. Research

Successful MMA betting requires analyzing fighter statistics like strikes and takedowns, recent form, style matchups, and training camps to identify value in the odds. Key factors include researching a fighter’s opponent quality, whether long layoffs matter, and overinflated lines.

4. Place your bet

Pick the fighter you want to win, or the method of victory you want them to win by, and enjoy the fights.

MORE: Beginner’s guide to parlay betting

Where to bet on UFC 334

If you’re looking to get in on the betting action for UFC 334 but are new to some of the best sportsbooks in your area, take advantage of new-user promos and welcome bonuses.

MORE: Best sportsbook promos and betting app bonuses

UFC 334 odds and best bets

The following odds are all courtesy of DraftKings Sportsbook.

Ciryl Gane (c) vs. Josh Hokit (Heavyweight title)

Gane vs. Hokit prediction and best bet

Gane lands 5.40 significant strikes per minute, landing 52 against Alex Pereira at the White House. He also averages 0.66 takedowns landed per 15 minutes. The French fighter can strike at close range and, if in the right frame of mind, can control the pace.

A Dana White’s Contender Series product, Hokit lands 9.29 significant strikes. Hokit landed 177 against Curtis Blaydes and 86 against Derrick Lewis. He also averages 3.73 takedowns landed, landing six in his octagon debut.

Hokit’s colorful personality may not be for everyone, but he backs it up in the octagon. What’s impressive: his explosive style and athleticism. Gane also shoots for takedowns. One thing to watch for with Gane: eye pokes and illegal strikes. However, before the former affected Tom Aspinall’s vision, Gane appeared to have control in the fight.

Hokit’s rise to the top has been admirable. His gas tank is impressive. However, despite several questions surrounding his skills, Gane is still on another level. He has the reach advantage (eight inches), elite striking, and a resume that trumps Hokit’s. There are still questions regarding Hokit’s defense, which may be his downfall in this fight.

Kayla Harrison (c) vs. Amanda Nunes (Bantamweight title)

Harrison vs. Nunes prediction and best bet

Harrison, the two-time Olympic gold medalist in judo, has eight submission wins and six knockout wins. The former PFL champion dominated former champion Holly Holm, overwhelmed Ketlen Vieira and decimated Julianna Pena. She averages 2.84 takedowns landed per 15 minutes and lands 4.29 significant strikes per minute.

Nunes is one of the most dangerous fighters in MMA history. Outside of being outstruck by Julianna Pena 79-46 in 2021, Nunes’ offensive output is something else, landing 4.55 significant strikes. She also averages 2.71 takedowns landed, executing 12 in her last two bouts.

It’s an intriguing matchup based on the circumstances. Nunes is coming off a three-year retirement. When they were expected to fight in January, the fight may have been easy to predict. Months later, Harrison is coming off a significant surgery to her neck.

Nunes will look to apply pressure early and control the center of the octagon. Even after all that time off, Harrison would be wise not to box against one of the best strikers in the game. Harrison likes to play it close to force her opponents to the floor. Can she work past Nunes’ 82% defense mark? And if she gets hit close to the neck, how will that affect Harrison?

The odds may still be in Harrison’s favor, but they aren’t as egregious as Nunes’ odds against Ronda Rousey all those years ago. When motivated, Nunes sees red and pounces on the opposition. If she can damage Harrison early, Nunes should return to the top of the mountain.

Caio Borralho vs. Yousri Belgaroui (Middleweight)

Borralho vs. Belgaroui prediction and best bet

Borralho lands 3.47 significant strikes per minute and averages 1.25 takedowns landed per 15 minutes. He landed 153 significant strikes against Jared Cannonier and beat Reinier de Ridder via decision.

Belgaroui had a second chance on Dana White’s Contender Series and has succeeded. The kickboxer lands 6.44 significant strikes and averages 0.27 takedowns landed. He’s won four straight octagon fights via knockout.

Belgaroui is four inches taller and can easily win if the fight is a shootout. However, Borralho should be smart enough to know that’s not how the fight should go. He can get Belgaroui against the cage and to the ground. With a clear grappling advantage, Borralho should be able to hold off “The Boogeyman.”

Uros Medic vs. Kevin Holland (Welterweight)

Medic vs. Holland prediction and best bet

Medic lands 5.77 significant strikes per minute. Six straight fights have ended via knockout in the first round. Holland lands 4.24 significant strikes and averages 0.79 takedowns landed per 15 minutes.

It has been said many times: the active Holland is either on another level in the cage or one of the most frustrating fighters out there. He can put Vicente Luque in an Anaconda Choke or look lost against Reinier de Ridder. Holland must remain consistent against a fighter as dangerous as “The Doctor.”

Medic will likely push the pace early to make Holland uncomfortable. However, Holland can use his 10-inch reach advantage and range to avoid Medic’s strikes. Playing it safe, using clinching and a few takedowns, would be smart for Holland, who should do enough to get the win.

Bilal Hasan vs. Luis Gurule (Flyweight)

Hasan vs. Gurule prediction and best bet

A product of Dana White’s Contender Series, Hasan has two knockout wins in 2026. He averages 1.83 takedowns landed per 15 minutes. Another DWCS alum, Gurule is 1-2 in 2026. He lands 5.44 significant strikes per minute but absorbs 5.35 strikes.

Hasan has the reach advantage and has all the momentum. The UFC sees something in the 25-year-old, given the matchup. Gurule shouldn’t be taken lightly, but the exciting Hasan should earn the win via stoppage.

UFC 334 prelims and full card

Main Card

• Ciryl Gane (c) vs. Josh Hokit for the UFC heavyweight title
• Kayla Harrison (c) vs. Amanda Nunes for the UFC bantamweight title
• Caio Borralho vs. Yousri Belgaroui; Middleweights
• Uros Medic vs. Kevin Holland; Welterweights
• Bilal Hasan vs. Luis Gurule; Flyweights

Prelims

• Stephen Thompson vs. Charles Radtke; Welterweights
• Drew Dober vs. Chris Duncan; Lightweights
• Jim Miller vs. Terrance McKinney; Lightweights
• Donte Johnson vs. Cesar Almeida; Middleweights

Early Prelims

• Jared Gordon vs. Melquizael Costa; Lightweights
• Macy Chiasson vs. Beatriz Mesquita; Bantamweights
• Alateng Heili vs. Juan Diaz; Bantamweights
• Evan Elder vs. Samuel Sanches; Lightweights