With another loaded slate this weekend, football fans have plenty of opportunities to capitalize on prediction markets this weekend in Week 6.

Sunday delivers several high-stakes games. The Dallas Cowboys and Green Bay Packers headline Sunday Night Football in a matchup featuring two NFC contenders, while the Los Angeles Chargers face the undefeated Kansas City Chiefs in a critical AFC West showdown.

Elsewhere, the Buffalo Bills take on the Las Vegas Raiders, and the Baltimore Ravens meet the Cleveland Browns in a physical AFC North battle. With plenty of opportunities for statement wins and potential upsets, here are our predictions for the biggest games of NFL Week 6.

Prediction markets are a great way for NFL and all sports fans to choose “Yes” or “No” answers on a team, player or game outcomes. It completely negates having to decode what sports betting odds are and what each line entails. 

Now is the perfect time for sports fans to use prediction markets with the NFL, MLB playoffs, NHL, college football and WNBA playoffs all in full swing. Plus, new users can get started with the TSN promo code for a $75 prediction bonus on ProphetX.

Here are the best prediction market apps to use for Week 6’s NFL slate, including the best offers and information about each platform.

MORE: A complete guide for using ProphetX

NFL Week 6 prediction market offers

Platform Current offer Fees
ProphetX Trade $50, get $75 2% commission on WINS ONLY
OG.com Trade $10, get $10 5% taker fee for sports
Kalshi Trade $25, get $25 $0.07 – $1.75 per 100 contracts
Polymarket Deposit $10, get $50 $0.02 per contract

ProphetX prediction market offer

ProphetX is one of the best up-and-coming prediction markets in the country, and the new user promo code is a big reason for that status. Currently, first-time players on ProphetX can claim a generous welcome offer at sign-up to trade $50 and get $75 in bonus funds.

Once applying the TSN promo code, new users must trade $50 on any qualifying market to receive the bonus reward. The $75 bonus will be paid out in three $25 increments over 14 days. With the welcome bonus awarded right out of the gate, new players can have the ability to continue wagering on the ProphetX platform using incentive funds rather than having to make an additional deposit right away.

PROPHETX: New users can use promo code TSN to trade $50 and get $75 in incentive funds

OG.com prediction market offer

On OG.com, new users can trade $10 and get $10 on the prediction platform.

This is exclusive to new accounts that are verified as 18 years old and reside in the United States. Availability varies by state, and other terms and conditions may apply.

How to trade NFL Week 6 with prediction markets

Trading on NFL Week 6 is a simple process for users to take part in. Here’s a step-by-step guide on how to trade in on the action:

  1. (if applicable) Create a prediction market account: Users must choose which prediction market to create an account with. 
  2. (if applicable) Verify your account and deposit: Once users set up their account with verification details and deposit funds, they can move on to making a prediction.
  3. Find the NFL section: This location varies across the market, but this can usually be found on the top or side navigation bar.
  4. Locate a desirable game and market: Now that you’ve made it to the NFL tab, you’ll be presented with games that can be predicted on. Click on a matchup and find a market (game lines, player props, etc.). Good luck!

MORE: Where prediction markets are legal in 2026

ProphetX NFL Week 6 prediction markets

ProphetX has an extensive selection of available markets for Week 6 of this year’s NFL campaign. As a reminder for those used to sports betting, ProphetX displays market percentages instead of betting odds. The percentages reflect the collective implied probability of an event. Meanwhile, betting odds are set by the house to bake in a profit margin.

Here’s an outline of some markets users can predict on:

  • Game lines (moneyline, spread, game total)
  • Team totals
  • TD props (TD scorers, first/last TD, passing TDs)
  • Passing props (passing TDs, yards, completions, interceptions, longest pass)
  • Rushing props (yards, attempts, longest rush)
  • Receiving props (yards, receptions, longest reception)
  • Combo props (passing + rush yards, rushing + receiving yards, tackles + assists)
  • Defensive props (tackles, assists, sacks)
  • Kicking props (kicking points, field goals made)
  • Quarter/Half props (moneyline, spread, total)

MORE: Promo code TSN gets you $75 in investment funds when you trade $50 on ProphetX

ProphetX NFL Week 6 value plays

The Carolina Panthers -5 is an appealing pick with Jalen Hurts ruled out for Philadelphia. The Eagles will have to rely on backup quarterback Tanner McKee, who hasn’t played this season, creating a major question mark under center. Philadelphia is also coming off three straight losses, and the absence of its starting quarterback makes it even harder to turn things around. Carolina can capitalize by pressuring McKee, forcing mistakes, and controlling the pace of the game. If the Panthers play disciplined football and capitalize on Philadelphia’s quarterback situation, they have a strong opportunity to win by more than a field goal and cover the five-point spread.

MORE: How do prediction market fees work?

Bernard going over 42.5 receiving yards is a risky play, but his recent breakout performance gives the over some appeal. The Pittsburgh Steelers rookie erupted for 80 receiving yards against Indianapolis in Week 5, showing the upside to produce well above this line. He has also recorded 20 receptions this season, giving him a path to clear 42.5 yards if his target volume increases. If Bernard can build on his latest performance and create a few plays downfield, he has the potential to surpass this number against Tampa Bay.

Henry’s 89.5 rushing yards are appealing because of his heavy workload and ability to break off explosive runs. Henry has recorded 24 or more carries in three of his first five games this season and is averaging 95.2 rushing yards per game. He is coming off a 102-yard performance against Atlanta and has already surpassed this line twice this season. With Baltimore continuing to lean on its star running back, Henry has a strong opportunity to reach the 90-yard mark against Cleveland.

MORE: Everything to know about the ProphetX promo code

Bowers has quickly established himself as the focal point of the Las Vegas Raiders’ passing attack. He has recorded at least eight catches in each of his three games this season, totaling 24 receptions on 35 targets. He is coming off an eight-catch, 110-yard performance against New England and faces a Buffalo defense that has struggled to contain opposing passing attacks. With Kirk Cousins frequently targeting him, Bowers has a strong opportunity to reach seven receptions or more in Week 6.

Kalshi NFL Week 6 markets

Of course, Kalshi offers their own batch of markets for Week 6 as well. They’re outlined here:

  • Game lines (moneyline, spread, game total)
  • Team totals (points, FGs, yards, safety, sacks)
  • Game props (first team to score, win margin, both teams to score)
  • TD props (anytime TDs, first TD, player to score team’s TD, defensive TD)
  • Passing props (passing TDs, yards, completions, attempts, interceptions)
  • Rushing props (yards, attempts, longest rush, most rushing yards)
  • Receiving props (yards, receptions, longest reception, most receiving yards)
  • Combo props (rushing + receiving yards)
  • Quarter/Half props (moneyline, spread, total)
  • Other props (fantasy points, race to points, overtime, tie)

MORE: Complete guide to using Kalshi

OG.com NFL Week 6 prediction markets

OG.com also has a solid list of markets for users to make predictions on. Here’s what platform users can decide on for this week of gridiron action:

  • Game lines (moneyline, spread, game total)
  • TD props (anytime TD, first TD, 2+, 3+)
  • Passing props (passing TDs, yards, completions, interceptions)
  • Rushing props (yards, attempts)
  • Receiving props (yards, receptions, longest reception)
  • Combo props (passing + rush yards, rushing + receiving yards)
  • Quarter/Half props (moneyline, spread, total)

MORE: New users on OG.com can trade $10 to get $10 using code TSN25

OG.com NFL Week 6 value plays

Washington has recorded 83, 98, and 124 receiving yards in three of his five games this season, averaging 70.4 yards per game. He is coming off a breakout 124-yard performance against Philadelphia, and his 16.0 yards per reception show he can clear this line with just a handful of catches. If Washington continues to see consistent targets from Trevor Lawrence, he has a strong chance to surpass 59.5 receiving yards.

Wilson under 69.5 receiving yards is an intriguing play against the New England Patriots in Week 6, especially with cornerback Christian Gonzalez potentially shadowing him. Gonzalez has the coverage skills to make life difficult for opposing No. 1 receivers, using his physicality and instincts to limit separation and disrupt passing lanes. If Gonzalez can prevent Wilson from making explosive plays downfield, the Jets wideout could struggle to reach 70 receiving yards. With New England looking to contain New York’s top offensive weapon, the under is worth considering.

MORE: Which prediction market app is best for sports?

Baltimore has looked stronger on both sides of the ball. The Ravens are coming off an impressive 30-23 overtime win over Atlanta, with Tyler Huntley leading a late comeback despite Lamar Jackson’s absence. Jackson could return this week, giving Baltimore’s offense an additional boost if he is cleared to play. Cleveland, meanwhile, is coming off a disappointing loss to the Jets and has several key players dealing with injuries. If the Ravens continue generating offensive success and take advantage of Cleveland’s injury concerns, they have a strong chance to win by at least five points and cover the spread.

Polymarket NFL Week 6 markets

Finally, it’s time to look at what markets Polymarket is offering for this slate of Thursday, Sunday, and Monday night games. Here’s what users can predict on:

  • Game lines (moneyline, spread, game total)
  • Team totals (TDs, yards, FGs)
  • Game props (race to points, first to score points, first to score TD, margin of victory, defensive TD, 2-point conversion, safety, overtime)
  • TD props (anytime TDs, first TD, player to score team’s TD, defensive TD)
  • Passing props (passing TDs, yards, completions, attempts, interceptions)
  • Rushing props (yards, attempts)
  • Receiving props (yards, receptions, longest reception)
  • Combo props (scrimmage yards)
  • Quarter/Half props (moneyline, spread, total)
  • Other props (fantasy points)

MORE: What to know about Polymarket prediction markets

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