The D/ST position in fantasy football can be overlooked, but selecting the right defense can be the difference between winning and losing in your playoffs.

Avoid deploying a top NFL defense in tough matchups, as it might not score points for the D/ST position. The best strategy is to focus solely on matchups — even in the fantasy playoffs.

If you have advanced this far in the season, you might’ve drafted an elite defense or played the streamer game successfully. Which direction should you take in your league’s semifinals?

Here are our Week 16 D/ST fantasy rankings, best starts, sleepers, and some matchups to avoid.

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Week 16 Fantasy D/ST Rankings: Start-sit team defense lineup tips

Rk Team Defense OPP
1 Houston Texans LV
2 Philadelphia Eagles @WAS
3 San Francisco 49ers @IND
4 Denver Broncos JAX
5 Green Bay Packers  @CHI
6 Chicago Bears GB
7 Seattle Seahawks LAR
8 Kansas City Chiefs @TEN
9 Indianapolis Colts SF
10 Jacksonville Jaguars  @DEN
11 Los Angeles Rams  @SEA
12 Buffalo Bills @CLE
13 Tampa Bay Buccaneers @CAR
14 Detroit Lions PIT
15 Atlanta Falcons @ARI
16 New Orleans Saints NYJ
17 Carolina Panthers TB
18 Cleveland Browns BUF
19 Arizona Cardinals ATL
20 Baltimore Ravens NE
21 Los Angeles Chargers @DAL
22 Pittsburgh Steelers  @DET
23 Minnesota Vikings @NYG
24 New York Jets @NO
25 New England Patriots @BAL
26 New York Giants MIN
27 Dallas Cowboys LAC
28 Miami Dolphins CIN
29 Tennessee Titans KC
30 Las Vegas Raiders @HOU
31 Washington Commanders PHI
32 Cincinnati Bengals @MIA

Who are the best fantasy defenses in Week 16?

There should be little debate that the Houston Texans are by far the best defensive unit in football. They’re so elite that starting them regardless of the matchup is a viable option. Luckily for those with the Houston defense, they face the Raiders, a favorable matchup. 

The Eagles have struggled, no doubt, but not defensively. In Week 16, they’ll face the Commanders, who have looked decent with Mariota, but still should be a game the Eagles win. 

Who are the top fantasy D/ST sleepers in Week 16?

By no means have the Buffalo Bills been elite this season on the defensive side of the football, but this matchup with the Browns is too good not to exploit. 

There’s a world where the Tennessee Titans’ defense holds strong against a Chiefs team likely without Patrick Mahomes. It’s risky for the fantasy playoffs, but it’s an option. 

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