No. 10 Vanderbilt welcomes No. 15 Missouri to Nashville on Saturday afternoon for a clash that could shake up both the SEC standings and the College Football Playoff picture.

It’ll mark the 17th all-time meeting between the former SEC East rivals, and the last one until 2027, when the league officially jumps to a nine-game conference schedule. Missouri has long had the upper hand in this matchup, holding a 12-4-1 series lead and riding a four-game winning streak over the Commodores. Three of those victories came by comfortable margins of at least two scores.

However, this isn’t the same old Vanderbilt squad. The Commodores took Missouri to double overtime last season and look like a team on a mission this time around. They enter the weekend fresh off a gritty 31-24 win over LSU, their second victory against a top-15 opponent this year, and have yet to taste defeat at home. With the Tigers rolling into town, Vanderbilt’s hoping to prove that the tide in this rivalry might just be turning.

Here’s what you need to know to watch Vanderbilt vs. Missouri, including start time and TV channel.

What channel is Vanderbilt vs. Missouri on?

Vanderbilt vs. Missouri will air nationally on ESPN, with Bob Wischusen (play-by-play) and Louis Riddick (color analyst) on the game call.

The game will also be available to stream on ESPN app and Fubo.

Now you can watch ESPN without cable. Stream live NBA, NFL, MLB, NHL, college sports, plus SportsCenter, First Take, and all your favorite ESPN shows—anytime, anywhere—only in the new ESPN app.

Vanderbilt vs. Missouri start time

  • Date: Saturday, October 25, 2025
  • Start Time: 3:30 p.m. ET or 12:30 p.m. PT 

Kickoff of Vanderbilt vs. Missouri is set for 3:30 p.m. ET or 12:30 p.m. PT on Saturday, October 25, 2025. 

The game will be played at FirstBank Stadium in Nashville, Tennessee.

Vanderbilt vs. Missouri radio station

Listen live to Vanderbilt vs. Missouri on SiriusXM via both channel 201 (Mississippi State broadcast) and channel 190 (Texas broadcast).

New subscribers can enjoy SiriusXM for free for four months. Listen to live NBA, NFL, MLB, and NHL games, plus NASCAR, college sports, and more. Stay updated with all the news and get all the analysis on multiple sport-specific channels.

Vanderbilt Commodores 2025 upcoming schedule

Here are Vanderbilt’s next five games:

Date Opponent Time (ET)
Oct. 25 vs. Missouri 3:30 p.m.
Nov. 1 at Texas 12:00 p.m.
Nov. 8 vs. Auburn TBD
Nov. 22 vs. Kentucky TBD
Nov. 29 at Tennessee TBD

Missouri Tigers 2025 upcoming schedule

Here are Missouri’s next five games:

Date Opponent Time (ET)
Oct. 25 at Vanderbilt 3:30 p.m.
Nov. 8 vs. Texas A&M TBD
Nov. 15 vs. Mississippi State TBD
Nov. 22 at Oklahoma 1:00 p.m.
Nov. 29 at Arkansas TBD

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