JUMP TO:

NFL Week 4 kicks off with a divisional showdown in the desert between two 2-1 teams.

The Seattle Seahawks and Arizona Cardinals have both gotten off to strong starts in the 2025 season, and their clash on Thursday Night Football has major implications for the NFC West. While it’s early in the season, this game will be a crucial step in their playoff aspirations, especially since both of their lone losses have come at the hands of a division rival in the San Francisco 49ers.

The Seahawks have a revamped offense in year two of the Mike Macdonald era. Seattle has a new quarterback at the helm in 2025 in Sam Darnold, who threw for a career-high 4,319 yards and 35 touchdowns in 2024 with the Minnesota Vikings. Along with Darnold, Seattle traded for former triple-crown winner Cooper Kupp to pair alongside star wideout Jaxson Smith-Njigba, who has over 96 yards in all three games this season.

On the other side, Arizona opened the season with two straight wins over the New Orleans Saints and Carolina Panthers before losing to San Francisco in Week 3. The Cardinals’ offense suffered a major blow when James Conner sustained an ankle injury that will sideline him for the remainder of the season, but there are still plenty of offensive pieces at quarterback Kyler Murray’s disposal, including Trey McBride and Marvin Harrison Jr. 

Both teams will look to grab their first NFC West win of the season on Thursday night and advance to 3-1. Follow along for updates throughout the game below.

STREAM: Watch Seahawks vs. Cardinals live with Amazon Prime

Seahawks vs. Cardinals score

 

NFL HQ: Live NFL scores | Updated NFL standings | Full NFL schedule

Seahawks vs. Cardinals live updates, highlights from ‘Thursday Night Football’

7:10 p.m.: Players have started to take the field for warmups. This includes Cardinals’ signal-caller Kyler Murray and wide receiver Marvin Harrison Jr., who are both dressed to match the Arizona sand theme.

Harrison Jr. has not had a great start to the 2025 season, capped off with a big drop in Week 3 against the San Francisco 49ers. He hopes to bounce back tonight.

6:53 p.m.: Seattle has also announced its inactives for the Week 4 matchup against Arizona.

Zach Charbonnet, who was questionable throughout the week with a foot injury, is officially active. 

6:50 p.m.: The Cardinals have officially posted their inactives for Thursday Night Football.

Most notable is Will Johnson, who Arizona selected in the second round of the 2025 NFL Draft, who is out with a groin injury. 

6:42 p.m.: Expect celebrities in the house for a primetime matchup, and that includes Peter Herbstreit.

Peter, who accompanies Kirk on his broadcasting trips, has taken the field in Arizona.

Herbstreit is a color analyst for tonight’s game, then will be traveling to Happy Valley, Pa. for ESPN’s “College GameDay” on Saturday morning. Right after, he’ll be going down to Athens, Ga. for a primetime kickoff between No. 17 Alabama and No. 5 Georgia. Kirk and Peter will travel over 4,200 miles.

6:41 p.m.: We’re only a few hours away from kickoff, and State Farm Stadium looks different.

As part of the NFL’s “rivalry uniforms” release, the Cardinals will be wearing their sand-colored uniforms. So, the field in Glendale had to match.

On the other side, Seattle will be wearing its traditional navy blue jerseys with “wolf grey” pants.

MORE SEAHAWKS-CARDINALS NEWS:

Where to watch Seahawks vs. Cardinals

Seahawks vs. Cardinals start time 

  • Date: September 26
  • Time: 8:15 p.m. ET

This is both teams’ first primetime game of the season. It will kickoff at 8:15 p.m. ET from State Farm Stadium in Glendale, Ariz.

What channel is Seahawks vs. Cardinals on?

Seahawks vs Cardinals will be Week 4’s edition of “Thursday Night Football,” on Amazon Prime Video. Al Michaels and Kirk Herbstreit are on the call. Kaylee Hartung will be on the sidelines.

Fans in Phoenix can watch the game on Fox, while those in the Seattle area can also tune in on Seahawks.com and the Seahawks app.

Seahawks schedule 2025

Week Date Matchup Time TV/Result
1 9/7 vs 49ers 4:25 p.m. ET 49ers 17, Seahawks 13
2 9/14 at Steelers 1:00 p.m. ET Seahawks 31, Steelers 17
3 9/21 vs Saints 4:05 p.m. ET Seahawks 44, Saints 13
4 9/25 at Cardinals 8:15 p.m. ET Amazon Prime Video
5 10/5 vs Buccaneers 4:05 p.m. ET CBS
6 10/12 at Jaguars 1:00 p.m. ET Fox
7 10/20 vs Texans 10:00 p.m. ET ESPN
8 BYE – – –
9 11/2 at Commanders 8:20 p.m. ET NBC
10 11/9 vs Cardinals  4:05 p.m. ET CBS
11 11/16 at Rams 4:05 p.m. ET Fox
12 11/23 at Titans 1:00 p.m. ET Fox
13 11/30 vs Vikings 4:05 p.m. ET Fox
14 12/7 at Falcons 1:00 p.m. ET Fox
15 12/14 vs Colts 4:25 p.m. ET CBS
16 12/18 vs Rams 8:15 p.m. ET Amazon Prime Video
17 TBD at Panthers TBD TBD
18 TBD at 49ers TBD TBD

Cardinals schedule 2025

Week Date Matchup Time TV/Result
1 9/7 at Saints 1:00 p.m. ET Cardinals 20, Saints 13
2 9/14 vs Panthers 4:05 p.m. ET Cardinals 27, Panthers 22
3 9/21 at 49ers 4:25 p.m. ET 49ers 16, Cardinals 15
4 9/25 vs Seahawks 8:15 p.m. ET Amazon Prime Video
5 10/5 vs Titans 4:05 p.m. ET CBS
6 10/12 at Colts 1:00 p.m. ET Fox
7 10/19 vs Packers 4:25 p.m. ET Fox
8 BYE – – –
9 11/3 at Cowboys 8:15 p.m. ET ABC / ESPN
10 11/9 at Seahawks 4:05 p.m. ET CBS
11 11/16 vs 49ers 4:05 p.m. ET Fox
12 11/23 vs Jaguars 4:05 p.m. ET CBS
13 11/30 at Buccaneers 1:00 p.m. ET Fox
14 12/7 vs Rams 4:25 p.m. ET Fox
15 12/14 at Texans 1:00 p.m. ET Fox
16 12/21 vs Falcons 4:05 p.m. ET Fox
17 TBD at Bengals TBD TBD
18 TBD at Rams TBD TBD
Share this post

Subscribe to our newsletter

Keep up with the latest blog posts by staying updated. No spamming: we promise.
By clicking Sign Up you’re confirming that you agree with our Terms and Conditions.

Related posts